Medical Assistant salary in Colorado
Updated Updated for 2026 tax law
A medical assistant in Colorado earns a median of $48,400 a year ($23.27/hour equivalent), 5.9% above the national median of $45,690. Colorado ranks #10 of 51 states. About 13,160 people do this job in Colorado.
Take-home pay in Colorado
At the Colorado median, a single filer keeps about $39,435 a year after federal, FICA and Colorado taxes — $1,517 every two weeks. Try your own numbers with the Colorado paycheck calculator.
- Gross pay
- $1,861.54
- Federal income tax
- −$139.54
- Social Security (6.2%)
- −$115.42
- Medicare (1.45%)
- −$26.99
- Colorado income tax
- −$54.66
- CO FAMLI
- −$8.19
- Take-home pay
- $1,516.74
Annual breakdown
- Gross
- $48,400
- Federal
- $3,628
- FICA
- $3,703
- State + local
- $1,634
- Net
- $39,435
- Marginal federal rate
- 12.0%
- Marginal state rate
- 4.4%
2026 federal brackets (Rev. Proc. 2025-32) and 2026 state rules. Estimates assume wages are your only income and use annual liability, so your actual withholding can differ slightly.
How Colorado compares
| Rank | State | Median salary |
|---|---|---|
| #1 | Washington | $59,290 |
| #2 | Alaska | $52,560 |
| #3 | District of Columbia | $51,050 |
| #4 | Minnesota | $50,480 |
| #5 | Oregon | $50,410 |
| #10 | Colorado | $48,400 |
| #49 | Louisiana | $36,320 |
| #50 | Alabama | $36,100 |
| #51 | Mississippi | $35,360 |
See the national medical assistant salary page for the full pay range and all states.
BLS occupation: Medical Assistants (SOC 31-9092), May 2025, state estimates.
Frequently asked questions
How much does a medical assistant make in Colorado?
The median salary is $48,400 a year and the average is $49,490 (BLS May 2025).
Is Colorado a good state for medical assistants?
Colorado ranks #10 of 51 states for median pay in this job, 6% above the national median of $45,690.
What is $48,400 after taxes in Colorado?
About $39,435 a year ($1,517 every two weeks) for a single filer in 2026.
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Estimates for information only — not tax, legal or financial advice.