Medical Assistant salary in Missouri
Updated Updated for 2026 tax law
A medical assistant in Missouri earns a median of $40,440 a year ($19.44/hour equivalent), 11.5% below the national median of $45,690. Missouri ranks #39 of 51 states. About 13,050 people do this job in Missouri.
Take-home pay in Missouri
At the Missouri median, a single filer keeps about $33,742 a year after federal, FICA and Missouri taxes — $1,298 every two weeks. Try your own numbers with the Missouri paycheck calculator.
- Gross pay
- $1,555.38
- Federal income tax
- −$102.80
- Social Security (6.2%)
- −$96.43
- Medicare (1.45%)
- −$22.55
- Missouri income tax
- −$35.84
- Take-home pay
- $1,297.75
Annual breakdown
- Gross
- $40,440
- Federal
- $2,673
- FICA
- $3,094
- State + local
- $932
- Net
- $33,742
- Marginal federal rate
- 12.0%
- Marginal state rate
- 4.7%
2026 federal brackets (Rev. Proc. 2025-32) and 2026 state rules. Estimates assume wages are your only income and use annual liability, so your actual withholding can differ slightly.
How Missouri compares
| Rank | State | Median salary |
|---|---|---|
| #1 | Washington | $59,290 |
| #2 | Alaska | $52,560 |
| #3 | District of Columbia | $51,050 |
| #4 | Minnesota | $50,480 |
| #5 | Oregon | $50,410 |
| #39 | Missouri | $40,440 |
| #49 | Louisiana | $36,320 |
| #50 | Alabama | $36,100 |
| #51 | Mississippi | $35,360 |
See the national medical assistant salary page for the full pay range and all states.
BLS occupation: Medical Assistants (SOC 31-9092), May 2025, state estimates.
Frequently asked questions
How much does a medical assistant make in Missouri?
The median salary is $40,440 a year and the average is $42,030 (BLS May 2025).
Is Missouri a good state for medical assistants?
Missouri ranks #39 of 51 states for median pay in this job, 11% below the national median of $45,690.
What is $40,440 after taxes in Missouri?
About $33,742 a year ($1,298 every two weeks) for a single filer in 2026.
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Estimates for information only — not tax, legal or financial advice.