Medical Assistant salary in South Carolina
Updated Updated for 2026 tax law
A medical assistant in South Carolina earns a median of $41,160 a year ($19.79/hour equivalent), 9.9% below the national median of $45,690. South Carolina ranks #37 of 51 states. About 12,110 people do this job in South Carolina.
Take-home pay in South Carolina
At the South Carolina median, a single filer keeps about $34,725 a year after federal, FICA and South Carolina taxes — $1,336 every two weeks. Try your own numbers with the South Carolina paycheck calculator.
- Gross pay
- $1,583.08
- Federal income tax
- −$106.12
- Social Security (6.2%)
- −$98.15
- Medicare (1.45%)
- −$22.95
- South Carolina income tax
- −$20.26
- Take-home pay
- $1,335.59
Annual breakdown
- Gross
- $41,160
- Federal
- $2,759
- FICA
- $3,149
- State + local
- $527
- Net
- $34,725
- Marginal federal rate
- 12.0%
- Marginal state rate
- 2.0%
2026 federal brackets (Rev. Proc. 2025-32) and 2026 state rules. Estimates assume wages are your only income and use annual liability, so your actual withholding can differ slightly.
How South Carolina compares
| Rank | State | Median salary |
|---|---|---|
| #1 | Washington | $59,290 |
| #2 | Alaska | $52,560 |
| #3 | District of Columbia | $51,050 |
| #4 | Minnesota | $50,480 |
| #5 | Oregon | $50,410 |
| #37 | South Carolina | $41,160 |
| #49 | Louisiana | $36,320 |
| #50 | Alabama | $36,100 |
| #51 | Mississippi | $35,360 |
See the national medical assistant salary page for the full pay range and all states.
BLS occupation: Medical Assistants (SOC 31-9092), May 2025, state estimates.
Frequently asked questions
How much does a medical assistant make in South Carolina?
The median salary is $41,160 a year and the average is $42,340 (BLS May 2025).
Is South Carolina a good state for medical assistants?
South Carolina ranks #37 of 51 states for median pay in this job, 10% below the national median of $45,690.
What is $41,160 after taxes in South Carolina?
About $34,725 a year ($1,336 every two weeks) for a single filer in 2026.
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Estimates for information only — not tax, legal or financial advice.