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Medical Secretary and Administrative Assistant salary in Colorado

Updated Updated for 2026 tax law

A medical secretary and administrative assistant in Colorado earns a median of $46,920 a year ($22.56/hour equivalent), 2.2% above the national median of $45,930. Colorado ranks #18 of 51 states. About 11,560 people do this job in Colorado.

Take-home pay in Colorado

At the Colorado median, a single filer keeps about $38,318 a year after federal, FICA and Colorado taxes — $1,474 every two weeks. Try your own numbers with the Colorado paycheck calculator.

Take-home pay (every 2 weeks)
$1,473.76
$38,318 per year · 18.3% total tax rate
Gross pay
$1,804.62
Federal income tax
−$132.71
Social Security (6.2%)
−$111.89
Medicare (1.45%)
−$26.17
Colorado income tax
−$52.16
CO FAMLI
−$7.94
Take-home pay
$1,473.76
Annual breakdown
Gross
$46,920
Federal
$3,450
FICA
$3,589
State + local
$1,563
Net
$38,318
Marginal federal rate
12.0%
Marginal state rate
4.4%

2026 federal brackets (Rev. Proc. 2025-32) and 2026 state rules. Estimates assume wages are your only income and use annual liability, so your actual withholding can differ slightly.

How Colorado compares

RankStateMedian salary
#1Washington$58,100
#2California$54,490
#3Massachusetts$50,290
#4Oregon$50,130
#5Minnesota$50,030
#18Colorado$46,920
#49Alabama$36,930
#50Louisiana$36,930
#51Mississippi$36,290

See the national medical secretary and administrative assistant salary page for the full pay range and all states.

BLS occupation: Medical Secretaries and Administrative Assistants (SOC 43-6013), May 2025, state estimates.

Frequently asked questions

How much does a medical secretary and administrative assistant make in Colorado?

The median salary is $46,920 a year and the average is $47,200 (BLS May 2025).

Is Colorado a good state for medical secretaries and administrative assistants?

Colorado ranks #18 of 51 states for median pay in this job, 2% above the national median of $45,930.

What is $46,920 after taxes in Colorado?

About $38,318 a year ($1,474 every two weeks) for a single filer in 2026.

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Estimates for information only — not tax, legal or financial advice.