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Medical Secretary and Administrative Assistant salary in Missouri

Updated Updated for 2026 tax law

A medical secretary and administrative assistant in Missouri earns a median of $43,980 a year ($21.14/hour equivalent), 4.2% below the national median of $45,930. Missouri ranks #35 of 51 states. About 12,260 people do this job in Missouri.

Take-home pay in Missouri

At the Missouri median, a single filer keeps about $36,425 a year after federal, FICA and Missouri taxes — $1,401 every two weeks. Try your own numbers with the Missouri paycheck calculator.

Take-home pay (every 2 weeks)
$1,400.95
$36,425 per year · 17.2% total tax rate
Gross pay
$1,691.54
Federal income tax
−$119.14
Social Security (6.2%)
−$104.88
Medicare (1.45%)
−$24.53
Missouri income tax
−$42.05
Take-home pay
$1,400.95
Annual breakdown
Gross
$43,980
Federal
$3,098
FICA
$3,364
State + local
$1,093
Net
$36,425
Marginal federal rate
12.0%
Marginal state rate
4.7%

2026 federal brackets (Rev. Proc. 2025-32) and 2026 state rules. Estimates assume wages are your only income and use annual liability, so your actual withholding can differ slightly.

How Missouri compares

RankStateMedian salary
#1Washington$58,100
#2California$54,490
#3Massachusetts$50,290
#4Oregon$50,130
#5Minnesota$50,030
#35Missouri$43,980
#49Alabama$36,930
#50Louisiana$36,930
#51Mississippi$36,290

See the national medical secretary and administrative assistant salary page for the full pay range and all states.

BLS occupation: Medical Secretaries and Administrative Assistants (SOC 43-6013), May 2025, state estimates.

Frequently asked questions

How much does a medical secretary and administrative assistant make in Missouri?

The median salary is $43,980 a year and the average is $44,070 (BLS May 2025).

Is Missouri a good state for medical secretaries and administrative assistants?

Missouri ranks #35 of 51 states for median pay in this job, 4% below the national median of $45,930.

What is $43,980 after taxes in Missouri?

About $36,425 a year ($1,401 every two weeks) for a single filer in 2026.

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Estimates for information only — not tax, legal or financial advice.