Medical Secretary and Administrative Assistant salary in South Carolina
Updated Updated for 2026 tax law
A medical secretary and administrative assistant in South Carolina earns a median of $40,170 a year ($19.31/hour equivalent), 12.5% below the national median of $45,930. South Carolina ranks #43 of 51 states. About 15,630 people do this job in South Carolina.
Take-home pay in South Carolina
At the South Carolina median, a single filer keeps about $33,955 a year after federal, FICA and South Carolina taxes — $1,306 every two weeks. Try your own numbers with the South Carolina paycheck calculator.
- Gross pay
- $1,545.00
- Federal income tax
- −$101.55
- Social Security (6.2%)
- −$95.79
- Medicare (1.45%)
- −$22.40
- South Carolina income tax
- −$19.30
- Take-home pay
- $1,305.96
Annual breakdown
- Gross
- $40,170
- Federal
- $2,640
- FICA
- $3,073
- State + local
- $502
- Net
- $33,955
- Marginal federal rate
- 12.0%
- Marginal state rate
- 2.0%
2026 federal brackets (Rev. Proc. 2025-32) and 2026 state rules. Estimates assume wages are your only income and use annual liability, so your actual withholding can differ slightly.
How South Carolina compares
| Rank | State | Median salary |
|---|---|---|
| #1 | Washington | $58,100 |
| #2 | California | $54,490 |
| #3 | Massachusetts | $50,290 |
| #4 | Oregon | $50,130 |
| #5 | Minnesota | $50,030 |
| #43 | South Carolina | $40,170 |
| #49 | Alabama | $36,930 |
| #50 | Louisiana | $36,930 |
| #51 | Mississippi | $36,290 |
See the national medical secretary and administrative assistant salary page for the full pay range and all states.
BLS occupation: Medical Secretaries and Administrative Assistants (SOC 43-6013), May 2025, state estimates.
Frequently asked questions
How much does a medical secretary and administrative assistant make in South Carolina?
The median salary is $40,170 a year and the average is $42,950 (BLS May 2025).
Is South Carolina a good state for medical secretaries and administrative assistants?
South Carolina ranks #43 of 51 states for median pay in this job, 13% below the national median of $45,930.
What is $40,170 after taxes in South Carolina?
About $33,955 a year ($1,306 every two weeks) for a single filer in 2026.
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Estimates for information only — not tax, legal or financial advice.