Nurse Practitioner salary in Mississippi
Updated Updated for 2026 tax law
A nurse practitioner in Mississippi earns a median of $124,730 a year ($59.97/hour equivalent), 5.7% below the national median of $132,300. Mississippi ranks #47 of 51 states. About 4,690 people do this job in Mississippi.
Take-home pay in Mississippi
At the Mississippi median, a single filer keeps about $92,262 a year after federal, FICA and Mississippi taxes — $3,549 every two weeks. Try your own numbers with the Mississippi paycheck calculator.
- Gross pay
- $4,797.31
- Federal income tax
- −$718.05
- Social Security (6.2%)
- −$297.43
- Medicare (1.45%)
- −$69.56
- Mississippi income tax
- −$163.74
- Take-home pay
- $3,548.53
Annual breakdown
- Gross
- $124,730
- Federal
- $18,669
- FICA
- $9,542
- State + local
- $4,257
- Net
- $92,262
- Marginal federal rate
- 24.0%
- Marginal state rate
- 4.0%
2026 federal brackets (Rev. Proc. 2025-32) and 2026 state rules. Estimates assume wages are your only income and use annual liability, so your actual withholding can differ slightly.
How Mississippi compares
| Rank | State | Median salary |
|---|---|---|
| #1 | California | $168,520 |
| #2 | New Jersey | $159,310 |
| #3 | Washington | $156,100 |
| #4 | Oregon | $155,680 |
| #5 | Alaska | $155,170 |
| #47 | Mississippi | $124,730 |
| #49 | Kentucky | $122,870 |
| #50 | Tennessee | $117,590 |
| #51 | Alabama | $105,750 |
See the national nurse practitioner salary page for the full pay range and all states.
BLS occupation: Nurse Practitioners (SOC 29-1171), May 2025, state estimates.
Frequently asked questions
How much does a nurse practitioner make in Mississippi?
The median salary is $124,730 a year and the average is $125,340 (BLS May 2025).
Is Mississippi a good state for nurse practitioners?
Mississippi ranks #47 of 51 states for median pay in this job, 6% below the national median of $132,300.
What is $124,730 after taxes in Mississippi?
About $92,262 a year ($3,549 every two weeks) for a single filer in 2026.
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Estimates for information only — not tax, legal or financial advice.