Nurse Practitioner salary in Missouri
Updated Updated for 2026 tax law
A nurse practitioner in Missouri earns a median of $129,930 a year ($62.47/hour equivalent), 1.8% below the national median of $132,300. Missouri ranks #35 of 51 states. About 7,710 people do this job in Missouri.
Take-home pay in Missouri
At the Missouri median, a single filer keeps about $94,904 a year after federal, FICA and Missouri taxes — $3,650 every two weeks. Try your own numbers with the Missouri paycheck calculator.
- Gross pay
- $4,997.31
- Federal income tax
- −$766.05
- Social Security (6.2%)
- −$309.83
- Medicare (1.45%)
- −$72.46
- Missouri income tax
- −$198.82
- Take-home pay
- $3,650.15
Annual breakdown
- Gross
- $129,930
- Federal
- $19,917
- FICA
- $9,940
- State + local
- $5,169
- Net
- $94,904
- Marginal federal rate
- 24.0%
- Marginal state rate
- 4.7%
2026 federal brackets (Rev. Proc. 2025-32) and 2026 state rules. Estimates assume wages are your only income and use annual liability, so your actual withholding can differ slightly.
How Missouri compares
| Rank | State | Median salary |
|---|---|---|
| #1 | California | $168,520 |
| #2 | New Jersey | $159,310 |
| #3 | Washington | $156,100 |
| #4 | Oregon | $155,680 |
| #5 | Alaska | $155,170 |
| #35 | Missouri | $129,930 |
| #49 | Kentucky | $122,870 |
| #50 | Tennessee | $117,590 |
| #51 | Alabama | $105,750 |
See the national nurse practitioner salary page for the full pay range and all states.
BLS occupation: Nurse Practitioners (SOC 29-1171), May 2025, state estimates.
Frequently asked questions
How much does a nurse practitioner make in Missouri?
The median salary is $129,930 a year and the average is $130,970 (BLS May 2025).
Is Missouri a good state for nurse practitioners?
Missouri ranks #35 of 51 states for median pay in this job, 2% below the national median of $132,300.
What is $129,930 after taxes in Missouri?
About $94,904 a year ($3,650 every two weeks) for a single filer in 2026.
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Estimates for information only — not tax, legal or financial advice.