Pharmacist salary in South Carolina
Updated Updated for 2026 tax law
A pharmacist in South Carolina earns a median of $135,700 a year ($65.24/hour equivalent), 3.7% below the national median of $140,910. South Carolina ranks #44 of 51 states. About 5,320 people do this job in South Carolina.
Take-home pay in South Carolina
At the South Carolina median, a single filer keeps about $97,913 a year after federal, FICA and South Carolina taxes — $3,766 every two weeks. Try your own numbers with the South Carolina paycheck calculator.
- Gross pay
- $5,219.23
- Federal income tax
- −$819.31
- Social Security (6.2%)
- −$323.59
- Medicare (1.45%)
- −$75.68
- South Carolina income tax
- −$234.77
- Take-home pay
- $3,765.88
Annual breakdown
- Gross
- $135,700
- Federal
- $21,302
- FICA
- $10,381
- State + local
- $6,104
- Net
- $97,913
- Marginal federal rate
- 24.0%
- Marginal state rate
- 5.2%
2026 federal brackets (Rev. Proc. 2025-32) and 2026 state rules. Estimates assume wages are your only income and use annual liability, so your actual withholding can differ slightly.
How South Carolina compares
| Rank | State | Median salary |
|---|---|---|
| #1 | Alaska | $167,310 |
| #2 | Oregon | $165,960 |
| #3 | California | $164,610 |
| #4 | Hawaii | $163,220 |
| #5 | Washington | $160,610 |
| #44 | South Carolina | $135,700 |
| #49 | Mississippi | $133,230 |
| #50 | Louisiana | $132,410 |
| #51 | Rhode Island | $128,180 |
See the national pharmacist salary page for the full pay range and all states.
BLS occupation: Pharmacists (SOC 29-1051), May 2025, state estimates.
Frequently asked questions
How much does a pharmacist make in South Carolina?
The median salary is $135,700 a year and the average is $136,730 (BLS May 2025).
Is South Carolina a good state for pharmacists?
South Carolina ranks #44 of 51 states for median pay in this job, 4% below the national median of $140,910.
What is $135,700 after taxes in South Carolina?
About $97,913 a year ($3,766 every two weeks) for a single filer in 2026.
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Estimates for information only — not tax, legal or financial advice.