Pharmacist salary in South Dakota
Updated Updated for 2026 tax law
A pharmacist in South Dakota earns a median of $146,790 a year ($70.57/hour equivalent), 4.2% above the national median of $140,910. South Dakota ranks #13 of 51 states. About 1,280 people do this job in South Dakota.
Take-home pay in South Dakota
At the South Dakota median, a single filer keeps about $111,597 a year after federal, FICA and South Dakota taxes — $4,292 every two weeks. Try your own numbers with the South Dakota paycheck calculator.
- Gross pay
- $5,645.77
- Federal income tax
- −$921.68
- Social Security (6.2%)
- −$350.04
- Medicare (1.45%)
- −$81.86
- South Dakota income tax
- $0.00No state income tax on wages
- Take-home pay
- $4,292.19
Annual breakdown
- Gross
- $146,790
- Federal
- $23,964
- FICA
- $11,229
- State + local
- $0
- Net
- $111,597
- Marginal federal rate
- 24.0%
- Marginal state rate
- 0.0%
2026 federal brackets (Rev. Proc. 2025-32) and 2026 state rules. Estimates assume wages are your only income and use annual liability, so your actual withholding can differ slightly.
How South Dakota compares
| Rank | State | Median salary |
|---|---|---|
| #1 | Alaska | $167,310 |
| #2 | Oregon | $165,960 |
| #3 | California | $164,610 |
| #4 | Hawaii | $163,220 |
| #5 | Washington | $160,610 |
| #13 | South Dakota | $146,790 |
| #49 | Mississippi | $133,230 |
| #50 | Louisiana | $132,410 |
| #51 | Rhode Island | $128,180 |
See the national pharmacist salary page for the full pay range and all states.
BLS occupation: Pharmacists (SOC 29-1051), May 2025, state estimates.
Frequently asked questions
How much does a pharmacist make in South Dakota?
The median salary is $146,790 a year and the average is $142,330 (BLS May 2025).
Is South Dakota a good state for pharmacists?
South Dakota ranks #13 of 51 states for median pay in this job, 4% above the national median of $140,910.
What is $146,790 after taxes in South Dakota?
About $111,597 a year ($4,292 every two weeks) for a single filer in 2026.
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Estimates for information only — not tax, legal or financial advice.