Physician Assistant salary in Missouri
Updated Updated for 2026 tax law
A physician assistant in Missouri earns a median of $135,130 a year ($64.97/hour equivalent), 0.6% below the national median of $135,880. Missouri ranks #22 of 51 states. About 2,300 people do this job in Missouri.
Take-home pay in Missouri
At the Missouri median, a single filer keeps about $98,214 a year after federal, FICA and Missouri taxes — $3,777 every two weeks. Try your own numbers with the Missouri paycheck calculator.
- Gross pay
- $5,197.31
- Federal income tax
- −$814.05
- Social Security (6.2%)
- −$322.23
- Medicare (1.45%)
- −$75.36
- Missouri income tax
- −$208.22
- Take-home pay
- $3,777.45
Annual breakdown
- Gross
- $135,130
- Federal
- $21,165
- FICA
- $10,337
- State + local
- $5,414
- Net
- $98,214
- Marginal federal rate
- 24.0%
- Marginal state rate
- 4.7%
2026 federal brackets (Rev. Proc. 2025-32) and 2026 state rules. Estimates assume wages are your only income and use annual liability, so your actual withholding can differ slightly.
How Missouri compares
| Rank | State | Median salary |
|---|---|---|
| #1 | New Jersey | $165,690 |
| #2 | California | $165,650 |
| #3 | Washington | $164,360 |
| #4 | Hawaii | $164,050 |
| #5 | New York | $160,880 |
| #22 | Missouri | $135,130 |
| #49 | Georgia | $115,390 |
| #50 | Mississippi | $105,920 |
| #51 | Alabama | $104,960 |
See the national physician assistant salary page for the full pay range and all states.
BLS occupation: Physician Assistants (SOC 29-1071), May 2025, state estimates.
Frequently asked questions
How much does a physician assistant make in Missouri?
The median salary is $135,130 a year and the average is $137,710 (BLS May 2025).
Is Missouri a good state for physician assistants?
Missouri ranks #22 of 51 states for median pay in this job, 1% below the national median of $135,880.
What is $135,130 after taxes in Missouri?
About $98,214 a year ($3,777 every two weeks) for a single filer in 2026.
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Estimates for information only — not tax, legal or financial advice.