Registered Nurse salary in Mississippi
Updated Updated for 2026 tax law
A registered nurse in Mississippi earns a median of $77,090 a year ($37.06/hour equivalent), 21.0% below the national median of $97,550. Mississippi ranks #50 of 51 states. About 29,060 people do this job in Mississippi.
Take-home pay in Mississippi
At the Mississippi median, a single filer keeps about $60,711 a year after federal, FICA and Mississippi taxes — $2,335 every two weeks. Try your own numbers with the Mississippi paycheck calculator.
- Gross pay
- $2,965.00
- Federal income tax
- −$312.68
- Social Security (6.2%)
- −$183.83
- Medicare (1.45%)
- −$42.99
- Mississippi income tax
- −$90.45
- Take-home pay
- $2,335.05
Annual breakdown
- Gross
- $77,090
- Federal
- $8,130
- FICA
- $5,897
- State + local
- $2,352
- Net
- $60,711
- Marginal federal rate
- 22.0%
- Marginal state rate
- 4.0%
2026 federal brackets (Rev. Proc. 2025-32) and 2026 state rules. Estimates assume wages are your only income and use annual liability, so your actual withholding can differ slightly.
How Mississippi compares
| Rank | State | Median salary |
|---|---|---|
| #1 | California | $140,270 |
| #2 | Hawaii | $136,320 |
| #3 | Oregon | $129,010 |
| #4 | Washington | $124,200 |
| #5 | Alaska | $109,480 |
| #49 | South Dakota | $78,060 |
| #50 | Mississippi | $77,090 |
| #51 | Alabama | $77,080 |
See the national registered nurse salary page for the full pay range and all states.
BLS occupation: Registered Nurses (SOC 29-1141), May 2025, state estimates.
Frequently asked questions
How much does a registered nurse make in Mississippi?
The median salary is $77,090 a year and the average is $78,950 (BLS May 2025).
Is Mississippi a good state for registered nurses?
Mississippi ranks #50 of 51 states for median pay in this job, 21% below the national median of $97,550.
What is $77,090 after taxes in Mississippi?
About $60,711 a year ($2,335 every two weeks) for a single filer in 2026.
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Estimates for information only — not tax, legal or financial advice.