Registered Nurse salary in Missouri
Updated Updated for 2026 tax law
A registered nurse in Missouri earns a median of $81,780 a year ($39.32/hour equivalent), 16.2% below the national median of $97,550. Missouri ranks #40 of 51 states. About 76,310 people do this job in Missouri.
Take-home pay in Missouri
At the Missouri median, a single filer keeps about $63,520 a year after federal, FICA and Missouri taxes — $2,443 every two weeks. Try your own numbers with the Missouri paycheck calculator.
- Gross pay
- $3,145.38
- Federal income tax
- −$352.37
- Social Security (6.2%)
- −$195.01
- Medicare (1.45%)
- −$45.61
- Missouri income tax
- −$109.30
- Take-home pay
- $2,443.10
Annual breakdown
- Gross
- $81,780
- Federal
- $9,162
- FICA
- $6,256
- State + local
- $2,842
- Net
- $63,520
- Marginal federal rate
- 22.0%
- Marginal state rate
- 4.7%
2026 federal brackets (Rev. Proc. 2025-32) and 2026 state rules. Estimates assume wages are your only income and use annual liability, so your actual withholding can differ slightly.
How Missouri compares
| Rank | State | Median salary |
|---|---|---|
| #1 | California | $140,270 |
| #2 | Hawaii | $136,320 |
| #3 | Oregon | $129,010 |
| #4 | Washington | $124,200 |
| #5 | Alaska | $109,480 |
| #40 | Missouri | $81,780 |
| #49 | South Dakota | $78,060 |
| #50 | Mississippi | $77,090 |
| #51 | Alabama | $77,080 |
See the national registered nurse salary page for the full pay range and all states.
BLS occupation: Registered Nurses (SOC 29-1141), May 2025, state estimates.
Frequently asked questions
How much does a registered nurse make in Missouri?
The median salary is $81,780 a year and the average is $85,900 (BLS May 2025).
Is Missouri a good state for registered nurses?
Missouri ranks #40 of 51 states for median pay in this job, 16% below the national median of $97,550.
What is $81,780 after taxes in Missouri?
About $63,520 a year ($2,443 every two weeks) for a single filer in 2026.
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Estimates for information only — not tax, legal or financial advice.