Registered Nurse salary in South Carolina
Updated Updated for 2026 tax law
A registered nurse in South Carolina earns a median of $82,360 a year ($39.60/hour equivalent), 15.6% below the national median of $97,550. South Carolina ranks #39 of 51 states. About 49,750 people do this job in South Carolina.
Take-home pay in South Carolina
At the South Carolina median, a single filer keeps about $63,625 a year after federal, FICA and South Carolina taxes — $2,447 every two weeks. Try your own numbers with the South Carolina paycheck calculator.
- Gross pay
- $3,167.69
- Federal income tax
- −$357.28
- Social Security (6.2%)
- −$196.40
- Medicare (1.45%)
- −$45.93
- South Carolina income tax
- −$120.97
- Take-home pay
- $2,447.12
Annual breakdown
- Gross
- $82,360
- Federal
- $9,289
- FICA
- $6,301
- State + local
- $3,145
- Net
- $63,625
- Marginal federal rate
- 22.0%
- Marginal state rate
- 5.2%
2026 federal brackets (Rev. Proc. 2025-32) and 2026 state rules. Estimates assume wages are your only income and use annual liability, so your actual withholding can differ slightly.
How South Carolina compares
| Rank | State | Median salary |
|---|---|---|
| #1 | California | $140,270 |
| #2 | Hawaii | $136,320 |
| #3 | Oregon | $129,010 |
| #4 | Washington | $124,200 |
| #5 | Alaska | $109,480 |
| #39 | South Carolina | $82,360 |
| #49 | South Dakota | $78,060 |
| #50 | Mississippi | $77,090 |
| #51 | Alabama | $77,080 |
See the national registered nurse salary page for the full pay range and all states.
BLS occupation: Registered Nurses (SOC 29-1141), May 2025, state estimates.
Frequently asked questions
How much does a registered nurse make in South Carolina?
The median salary is $82,360 a year and the average is $87,670 (BLS May 2025).
Is South Carolina a good state for registered nurses?
South Carolina ranks #39 of 51 states for median pay in this job, 16% below the national median of $97,550.
What is $82,360 after taxes in South Carolina?
About $63,625 a year ($2,447 every two weeks) for a single filer in 2026.
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Estimates for information only — not tax, legal or financial advice.